Dutasteride Is Effective for Patients with Benign Prostatic Hyperplasia in Hemodialysis

Hypothesis / aims of study Among dialysis patients urine production is kept, complaining of lower urinary tract symptoms (LUTS) are observed, some were reported underwent surgery for benign prostatic hyperplasia (BPH). However, there are many patients with complications having difficulty in surgery , it is often managed by a placement of catheter. Dutasteride (DUT) reduces prostate volume and improves LUTS by releasing the mechanical obstruction in the prostatic urethra. This drug is metabolized in the liver, is likely to be excreted in feces and has a possibility to use for dialysis patients. However, the reports of this drug used for dialysis patients has not been published as far as our knowledge, and there are many unanswered questions such as therapeutic effect, changes in hormone levels. In this report, we examined effectiveness and changes in hormone levels using DUT to the patients with hemodialysis, complaining of LUTS associated with BPH.